概述 |
| 品牌 | ReportBio |
货号
| RA8752 |
| 产品描述 | HLA B7 Rabbit Monoclonal antibody |
| 反应物种 | Human |
| 应用 | WB, IF/ICC, ELISA |
| 宿主 | Rabbit |
| 克隆 | Monoclonal
|
| 同位型 | IgG |
| 靶点名称 | HLA B7 |
| 免疫原 | Synthetic peptide. This information is considered to be commercially sensitive. |
| 偶联标记 | Unconjugated |
| 別名 | AS; HLAB; B-4901; HLA B7 |
| 应用说明 |
| 应用建议 | WB:1:1000 - 1:4000 , ICC/IF:1:50 - 1:200 ,Elisa:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
| 阳性对照 | A-431, HaCaT |
| 实际分子量 | 40 kDa |
属性
|
| 形式 | Liquid |
| 纯化 | Affinity purification |
| 缓冲液 | PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3. |
| 抗菌剂 | proclin300 or sodium azide (as specified on the Certificate of Analysis) |
| 稳定剂 | 0.05% BSA |
| 存放说明 | Store at -20℃. Avoid freeze / thaw cycles. |
| 注意事项 |
|
生物信息
|
| 数据库连接 |
GeneID: 3106 Human HLA-B Swiss-port # P01889 Human HLA class I histocompatibility antigen, B-7 alpha chain |
| 基因名称 | HLA-B |
| 全名 | major histocompatibility complex, class I, B |
| 背景介绍 | HLA-B7 allele of human HLA class I major histocompatibility (MHC) antigen indicates higher risk of breast cancer and cervical cancer. Expression of HLA-B7 together with HLA-B27 is associated with increased susceptibility to spondyloarthropaties. Flow cytometry detection of these two alleles is being used to screen for patients, who suffer from inflammatory disorders affecting the sacroiliac and intervertebral joints, such as ankylosing spondylosis (AS). The HLA-B7 antigen (11 alleles) is expressed in 22% of healthy Caucasian individuals. |
| 生物功能 | Involved in the presentation of foreign antigens to the immune system. [UniProt] |
| 预测分子量 | 40kDa
|
| 翻译后修饰 |
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