概述
品牌	ReportBio
货号	RA28686
产品描述	APC Rabbit anti-Human HLA-B Monoclonal Antibody
反应物种	Human
应用	FC (intra)
宿主	Rabbit
克隆	Monoclonal
同位型	IgG
靶点名称	HLA-B
抗原物种
抗原	Synthetic peptide. This information is considered to be commercially sensitive.
偶联标记	APC. Ex:650nm. Em:660nm.
別名	AS; HLAB; B-4901
应用说明
应用建议	FC（ intra）：5 μl per 10^6 cells in 100 μl volume
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照
实际分子量
属性
形式	Liquid
纯化	Affinity purification
缓冲液	PBS
抗菌剂	0.09% Sodium azide
稳定剂	0.2% BSA, pH7.3.
存放说明	Store at 2-8℃. Avoid freeze.
注意事项
生物信息
数据库连接	GeneID: 3106 Human HLA-B Swiss-port # P01889 Human HLA class I histocompatibility antigen, B-7 alpha chain
基因名称	HLA-B
全名	major histocompatibility complex, class I, B
背景介绍	The human leukocyte antigen (HLA) system is a gene complex encoding the major histocompatibility complex (MHC) proteins in humans. These cell-surface proteins are responsible for the regulation of antigen-specific immune responses in humans. HLA genes are highly polymorphic, which enables them to fine-tune the adaptive immune response. The class I HLA molecules (HLA-A, -B, and -C) present small peptide antigens, approximately 8 to 10 amino acids in length, originating from inside the cell to CD8+ cytotoxic T lymphocytes, thereby activating a cytotoxic T-cell response. The class II HLA molecules (HLA-DP, -DM, -DO, -DQ, and -DR) present antigens derived from outside the cell, approximately 15 to 24 residues in length, to CD4+ helper T cells. These helper T cells subsequently secrete cytokines and stimulate B cells to produce antibodies specific to that antigen. The class III HLA region encodes components of the complement system.
生物功能
细胞定位	Membrane; Single-pass type I membrane protein. [UniProt]
预测分子量	40kDa
翻译后修饰